Progesterone (P)

Progesterone iprogestogen inokosha, yehomoni dzesteroid, ine huremu hwema molecular huremu hwe314.5.Inonyanya kubudiswa ne corpus luteum ye ovary uye placenta panguva yekuzvitakura.Ndiyo inotangira testosterone, estrogen uye adrenal cortex mahomoni.Iyo progesterone level inogadzirwa panguva yefollicular chikamu cheyakajairika varume nevakadzi yakadzikira kwazvo, mushure mekuvharirwa muropa, inonyanya kusungwa kualbumin uye mahomoni ebonde anosunga mapuroteni uye anotenderera mumuviri.

Basa guru reprogesterone nderekuita kuti chibereko chigadzirire kuiswa kwemazai akabatanidzwa uye kuchengetedza pamuviri.Munguva yefollicular phase yekuenda kumwedzi, chiyero cheprogesterone chakaderera.Mushure mokunge ovulation, progesterone inobudiswa ne corpus luteum inowedzera nokukurumidza, uye inosvika pahuwandu hwehuwandu hwe10ng / mL-20ng / mL mumazuva 5-7 mushure mekuvhara.Kana isina kunambwa, iyo corpus luteum atrophies mukati memazuva mana ekupedzisira ekuenda kumwedzi uye kuwanda kweprogesterone kunoderera kusvika kufollicular phase.Kana ikaitwa pamuviri, corpus luteum haiperi uye inoramba ichibudisa progesterone, ichiichengeta pamazinga akaenzana nechepakati luteal phase uye ichienderera mberi kusvika vhiki yechitanhatu yekuzvitakura.Panguva yekuzvitakura, placenta zvishoma nezvishoma inova iyo huru yeprogesterone, uye kuwedzera kunowedzera kubva pa10ng / mL-50ng / mL mumwedzi mitatu yekutanga yekuzvitakura kusvika 50ng / mL-280ng / mL mumwedzi 7-9.Zvidzidzo zvekiriniki zvakaratidza kuti progesterone inobata basa mukusimudzira ovulation uye kuchengetedza yakajairika basa re corpus luteum muvakadzi vasina nhumbu.Kana iyo progesterone inogadzirwa ne corpus luteum isingakwanisi, inogona kuratidza kuti corpus luteum basa haina kukwana, uye iyo isina kukwana corpus luteum basa inobatana nekushaya mbereko uye kuparara kwepakutanga.